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DropCare® SD: The Advanced Selenium Disulfide Solution for Superior Dandruff Control

DropCare® SD: The Advanced Selenium Disulfide Solution for Superior Dandruff Control

December 31, 2025

In the world of scalp care and dandruff treatment, not all active ingredients are created equal. DropCare® SD (Selenium Disulfide) stands out as a clinically proven, highly effective solution for managing dandruff, seborrheic dermatitis, and associated scalp concerns. With a legacy of efficacy and safety backed by pharmacopoeial standards, it is the ingredient of choice for formulators aiming to create high-performance anti-dandruff products.

What is DropCare® SD?

DropCare® SD is a premium grade of Selenium Disulfide (SeS₂), a recognized active ingredient with keratolytic, antiseborrheic, antifungal, and antibacterial properties. Its INCI name is Selenium Disulfide, CAS No. 7488-56-4. It works by slowing down the excessive turnover of skin cells on the scalp, reducing scaling, relieving itching, and calming inflammation. Its inclusion in the Chinese Pharmacopoeia 2020 underscores its recognized therapeutic value in improving clinical symptoms and reducing recurrence rates in skin conditions.

Proven Efficacy Against Dandruff & Itch

Clinical studies demonstrate the superior performance of Selenium Disulfide. In a 28-day consumer trial, a shampoo containing 1% Selenium Disulfide showed remarkable results:

  • 93.3% of subjects reported a significant reduction or complete disappearance of dandruff.

  • 90.0% of subjects noted a marked improvement in scalp itch.

Instrumental analysis confirmed visible reduction in flakes and scalp irritation, proving its potent anti-dandruff and anti-itch benefits.

Superior to Other Common Actives

Comparative medical studies place Selenium Disulfide at the forefront of dandruff-fighting ingredients. After 28 days of use:

  • Selenium Disulfide reduced dandruff by 79.50% – outperforming other common agents.

  • Ketoconazole: 73% reduction

  • Piroctone Olamine (ZPT): 65.05% reduction

  • Salicylic Acid: 70.50% reduction

  • Climbazole: 63.50% reduction

This data clearly establishes Selenium Disulfide as one of the most effective choices for scalp flake reduction.

Gentle Yet Effective: The Amino Acid-Based Formula

Understanding the need for effective yet mild formulations, DropCare® SD can be seamlessly incorporated into gentle systems. Research into an amino acid-based shampoo containing Selenium Disulfide resulted in a product with a skin-friendly pH of approximately 5.5. This mild, weak acidic formulation minimizes hair damage while effectively treating seborrheic dermatitis. Long-term use over 42 days showed a consistent and significant decrease in dandruff severity.

Key Benefits & Product Features

  • Multi-Action Efficacy: Combats fungi and bacteria, reduces excess sebum fatty acids, and provides anti-inflammatory action.

  • Broad Application: Clinically valuable for treating scalp psoriasis, seborrheic dermatitis, tinea versicolor, and acne.

  • High Patient Compliance: Easy-to-use format in wash-off products promotes regular use and better treatment outcomes.

  • Synergistic Potential: Can be used in combination with oral medications to reduce overall treatment time and relapse rates.

  • Formulation Versatility: Suitable for development into various product forms, enabling innovation in the dandruff care market.

Conclusion

DropCare® SD (Selenium Disulfide) is more than just a dandruff ingredient; it is a versatile, potent, and trusted active with strong clinical credentials. Its proven superiority over other agents, combined with its adaptability into modern, gentle formulations like amino acid bases, makes it an exceptional choice for brands seeking to develop next-generation scalp care products that deliver visible, soothing results.

Choose DropCare® SD for formulations that offer exceptional efficacy, patient acceptance, and a clear competitive edge in the anti-dandruff market.

Please contactjudyzhou@drop-bio.com

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