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In the quest for breakthrough hydrators, Polyglutamic Acid (PGA) has emerged as a game-changer. But not all PGAs are created equal. At DropBio®, we engineered DropCare® PGA70 (700 kDa) and DropCare® PGA01 (10 kDa) to deliver targeted performance across all cosmetic formulations. Here’s why molecular weight matters:
Sodium Polyglutamate is a natural, fermentation-derived polymer with a unique γ-peptide bond structure (linking α-amino and γ-carboxyl groups). Its secret lies in:
5000%+ water-binding capacity (outperforming hyaluronic acid)
Dense carboxyl side chains forming H-bond networks
Biofilm-forming ability that locks moisture into skin
Property | DropCare® PGA70 (700 kDa) | DropCare® PGA01 (10 kDa) |
---|---|---|
Primary Function | Surface Film-Former | Deep Skin Penetrator |
Texture | Velvety-thick | Featherlight |
Key Benefits | • 24H barrier-locking hydration • Wrinkle-smoothing film • Enhances product spreadability |
• Boosts NMF synthesis • Transports actives deep into skin • Instant plumping effect |
Best For | Creams/Masks/Leave-on products | Serums/Toners/Rinse-off formulas |
Both variants deliver multi-mechanistic anti-aging results:
✅ 3X Hyaluronic Acid Boost (in-vivo data)
✅ 28% Reduction in TEWL after 4 weeks
✅ 19% Improvement in skin elasticity
✅ Melanin Inhibition for brightening
Creates breathable moisture-trapping mesh
Perfect for high-viscosity anti-aging creams
Use at 0.5-1.0% for cushion-like texture
Penetrates stratum corneum in <30 sec
Ideal for watery essences & boosters
Effective at 0.1-0.5% with zero tackiness
Pair them for synergistic effects:
Cleanser: PGA01 (0.2%) → Preps skin for absorption
Toner: PGA01 (0.3%) + PGA70 (0.1%) → Multi-depth hydration
Cream: PGA70 (0.8%) → Seals in active ingredients
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